School of Brain Cells & Circuits "Camillo Golgi"

Ettore Majorana Foundation and Centre for Scientific Culture, Erice (Italy)

Programme 2017

From cell physiology to integrated signals and emerging brain functions

Course Directors: Egidio D’Angelo, Claudia Gandini Wheeler-Kingshott & Nikos Logothetis

Date: 29th November – 3th December 2017


The 2017 Course of the School of Brain Cells and Circuits will be dedicated to current understanding of how the brain works, offering a platform to merge expertise from scientists working on cellular physiology, computational modeling and integrated brain signals using magnetic resonance imaging. Bringing together these communities, offering advanced teaching sessions on key topics will foster discussion on the origin of fMRI and discuss where bottom-up and top-down computational models can and need to meet to explain brain functions.

Wednesday 29-11-2017
Arrival and evening reception in the “Marsala cellar”

Thursday 30-11-2017
Physiological bases of brain function

8:30 – Introduction to the course.
“Where and how the bottom-up and top-down converge.”
Egidio D’Angelo (University of Pavia, Italy)

8:45 – “Neuronal dynamics and plasticity in brain microcircuits: on the way to explain ensemble functions”
Egidio D’Angelo (University of Pavia, Italy)

9:45 – “Effects of Neuromodulation on Neurovascular Coupling.
Daniel Zaldivar (Max Plank Institute, Tuebingen, Germany)

10:30-11:00 Coffee break & posters

11:45 – “Molecular/cellular level models of neurons.”
Michele Migliore (CNR Palermo, Italy)

12:30 – “Bottom-up brain modeling : the NEURON platform”
Michael Hines (Yale, USA)

13:15-15:00 Lunch

15:00 – “Microcircuits in action: towards bottom-up modeling of brain function.”
Claudia Casellato (University of Pavia, Italy) & Alessandra Pedrocchi (PoliMI, Italy)

15:45 – “The physiological basis of neurovascular coupling in brain microcircuits. “
Catherine Hall (University of Sussex, UK)

16:30-17:00 Coffee break & posters

17:00 – ” Cerebral blood flow modeling – Analyzing microvascular networks and their perfusion. “
Franca Schmid (Zurich, CH)

17:45 – “Up and down of striatal fMRI signals”
Yen-Yu Ian Shih (University of North Carolina, USA)

Friday 1-12-2017
Integrated brain functional signals.

8:30 – “Realistic modeling of neurovascular coupling. “
Shyam Diwakar (Amrita University, India)

9:15 – “What we can see but can’t explain: fMRI in vivo in humans.”
Claudia AM Gandini Wheeler-Kingshott (University College London, UK & University of Pavia, Italy)

10:00 – “Advanced fMRI: laminar fMRI at ultra high field”
Jozien Goense (Glasgow University UK)

10:45-11:15 Coffee break & posters

11:15 – “Insights on human brain function and microstructure using diffusion-weighted MR spectroscopy in vivo
Francesca Branzoli (ICM, France)

12:00 – “Quantification of changes in cerebral blood flow and oxygen metabolism using Arterial Spin Labeling.”
Laura Parkes (Manchester University, UK)

12:45-15:00 Lunch

15:00 – “Multi-parametric MR Imaging of the physiological state of brain tissue” 
Richard Wise (CUBRIC, UK)

15:45 – “Studying Spontaneous Human Activity Using fMRI Combined with EEG. “
Louis Lemieux (University College London, UK)

16:30 – “Functional MR spectroscopy for the exploration of neuroenergetics.”
Federico Giove (Centro Fermi, Italy)


Saturday 2-12-2017
Understanding emerging brain function.

9:00 – “Combining fMRI and computational modelling to understand cortical plasticity.”
Caroline Lea-Carnall (Manchester University, UK)

9:45 –“Translating models to clinics… Computational realistic models to investigate cerebellar pathologies”
Alessandra Pedrocchi (POLIMI, Italy)

10:15 –“How a model can generate Autistic behaviour”
Egidio D’Angelo (University of Pavia, Italy)

10:30-11:00 Coffee break & posters

11:00 – Summary “firing” talks from all speakers (5 min each). 
All speakers

12:30 – Debate
Top-down and bottom-up approaches to brain function and disease: where do they meet?

Lead discussants: Egidio D’Angelo (University of Pavia, Italy) & Marco Bozzali (Brighton & Sussex Medical School, UK)

Poster prize and adjournment

Sunday 03-12-2016

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