Programme 2015
Modeling the brain: from neurons to integrated systems
Course Directors: Egidio D’Angelo, Claudia Gandini Wheeler-Kingshott, Michele Migliore
The 2015 Course of the school of brain cells and circuits was dedicated to brain modeling and theory. Bottom-up models, descending from cellular and molecular biophysics, and top-down models, derived from neuropsychology and non-invasive brain measurements (mostly brain imaging using MRI), are both needed to integrate the micro-, meso and macro-scale of brain organization and to pilot future experimentation. Brain theories need to interface with new experimental measurements and cellular circuit models simulations. This approach requires merging expertise and knowledge deriving from different disciplines, from Physics and Mathematics to Biology, Psychology and Medicine. The 2015 Course gathered scientists providing an integrated view of this enormous field with the aim of teaching the foundations of brain modeling and theory.
Sunday 29-11-2015
Arrival and opening reception
Monday 30-11-2015
Biophysically detailed models of neurons and networks
Morning
Introduction
Egidio D’Angelo, Claudia Gandini Wheeler-Kingshott, Michele Migliore
Lectures
Erik DeSchutter (OIST, Okinawa, Japan)
“Stochastic effects in neurons at molecular and cellular levels”
Egidio D’Angelo (University of Pavia, Pavia, Italy)
“Complex dynamics in single neuron and microcircuit models”
Eilif Muller (EPFL, Lausanne, Switzerland)
“Reconstruction and simulation of cortical microcircuitry”
Afternoon
Practice – interactive demonstration
Michael Hines (YALE, USA) – Modeling in Python-NEURON
General discussion
Tuesday 1-12-2015
Large-scale models and theory
Morning
Lectures
Michele Migliore (CNR, Palermo, Italy)
“Odor perception through network self-organization: large-scale modeling of the olfactory bulb”
Michael Hines (YALE, USA)
“Parallel Network Modeling with NEURON”
Alain Destehxe (CNRS, France)
“Realistic mean-field models of neuronal populations”
Fabrizio Gabbiani (Baylor College, Huston, USA)
“Biophysics and Neural Computations Underlying Visually-Guided Collision Avoidance Behaviors”
Afternoon
Practice – interactive demonstration
Alessandra Pedrocchi & Alberto Antonietti (Milano, Italy) – Closed-loop robotic control using spiking neural networks
General discussion
Wednesday 2-12-2015
Models of brain systems: the connectome
Morning
Lectures
Claudia Gandini Wheeler-Kingshott (UCL, UK)
“The need for brain connectomic and the role of structural and functional MRI”
Shyam Diwakar (Amrita, India)
“From Network Models to Applications and Vice-versa: Cerebellum Network Models and their Abstractions”
Demian Battaglia (Aix Marseille Université, FR)
“From structural to functional connectivity networks, via emergent dynamics”
Martjin van der Heuvel (University Medical Center, Utrecht, Holland)
“Micro and macro network analysis of the connectome”
Eugene Duff (Oxford University, UK)
“Functional network modelling using fMRI”
Afternoon
Practice – interactive demonstration
Demian Battaglia (Aix Marseille, France) & Eugene Duff (Oxford, UK) – Software for brain modeling & connectomics
General discussion and closure of the meeting
Thursday 3-12-2015
Departure
SPONSORS
Centro Fermi
http://www.centrofermi.it
HBP Education Programme
https://education.humanbrainproject.eu
Fondazione Istituto Neurologico Nazionale C. Mondino
Università di Pavia
http://www.unipv.eu/site/en/home.html
CNR
http://www.cnr.it/sitocnr/Englishversion/Englishversion.html
Siemens Healthcare S.r.l.
http://www.healthcare.siemens.it
Collegio Borromeo, Pavia (Italy)